dyspnea

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

---

Study Counts

Type	Study_count
Total_Studies	235
interventional	164
Observational	64
Registry	7

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Other	32
Device	31
Drug	24
Drug|placebo	21
Behavioral	17
Procedure	14
Device|Other	5
Diagnostic Test	4
Behavioral|Drug|Other|placebo	2
Behavioral|Other	2
Drug|Other|placebo	2
Other|Procedure	2
Behavioral|Device|Drug|Other|placebo	1
Behavioral|Drug|placebo	1
Behavioral|Drug|Procedure	1
Device|Drug|placebo	1
Device|Procedure	1
Other|placebo	1
Other|placebo|Procedure	1
Other|Procedure|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	55
Canada	20
France	14
Denmark	8
NA	7
United Kingdom	7
Brazil	5
Germany	5
Netherlands	4
Spain	4
China	3
Finland	3
Italy	3
Korea, Republic of	2
Sweden	2
Turkey	2
Australia	1
Australia|New Zealand	1
Belgium	1
Belgium|Canada|Germany|Netherlands	1
Belgium|Canada|Germany|Spain|United Kingdom	1
Egypt	1
France|Germany|Italy|Latvia|Spain|United Kingdom	1
Germany|Switzerland	1
Ghana	1
Hong Kong	1
Iran, Islamic Republic of	1
Norway	1
Russian Federation|United Kingdom	1
Taiwan	1
Tunisia	1
United States|Australia|United Kingdom	1
United States|Canada	1
United States|Canada|China	1
United States|Canada|Korea, Republic of|Saudi Arabia	1
United States|Canada|New Zealand	1

Sites per Study

Site_count	Study_Count
1	116
2	19
3	10
4	2
5	3
7	1
8	1
9	2
10	1
13	1
15	2
16	1
18	1
19	1
39	1
43	1
167	1

Phase

Phase	Study_Count
N/A	102
Phase 2	14
Phase 3	14
Phase 4	13
Phase 1/Phase 2	7
Phase 2/Phase 3	6
Phase 1	5
Early Phase 1	3

Number of Arms

Number_of_Arms	Count_of_Studies
1	30
2	107
3	9
4	5
6	1
12	1
NA	11

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	14.00000	7.0000	12.0	23.00000	8.00000	24.00	15.0000	15.00000
1st Qu.	22.00000	31.2500	16.0	24.00000	23.75000	33.75	23.0000	20.00000
Median	30.00000	60.0000	25.0	26.00000	32.50000	175.50	116.0000	50.00000
Mean	44.66667	144.9804	35.6	49.42857	58.35714	206.50	123.3077	88.61538
3rd Qu.	60.00000	160.7500	25.0	62.00000	40.00000	378.00	208.0000	106.00000
Max.	90.00000	1611.0000	100.0	125.00000	360.00000	432.00	257.0000	366.00000

Trial Group Type

group_type	Group_Count
Experimental	160
Active Comparator	65
Placebo Comparator	36
No Intervention	28
NA	11
Other	10
Sham Comparator	10

Intervention Model

intervention_model	Study_Count
Parallel Assignment	78
Crossover Assignment	42
Single Group Assignment	38
Factorial Assignment	4
Sequential Assignment	2

Primary Purpose

primary_purpose	Study_Count
Treatment	83
Supportive Care	31
Diagnostic	26
Basic Science	7
Other	5
Health Services Research	4
Prevention	4
NA	3
Device Feasibility	1

Observational Studies

Studies by Country

Country	Study_Count
France	16
United States	12
Germany	4
Italy	4
Canada	3
Denmark	3
Tunisia	3
United Kingdom	3
Norway	2
Slovenia	2
Belgium	1
France|Lithuania	1
India|Sri Lanka	1
Malaysia	1
NA	1
Singapore	1
Sweden	1
Switzerland	1
Turkey	1
United States|Belgium	1
United States|Germany|Greece|Italy|New Zealand|Poland|Switzerland|United Kingdom	1
United States|Italy	1

Sites per Study

Site_count	Study_Count
1	45
2	7
3	5
4	3
7	1
9	1
15	1
177	1

Enrollment Metrics

Measure	Observational
Min	20.00
1st Qu	79.50
Median	271.00
Mean	2044.27
3rd Qu	612.00
Max	75000.00

Observation Model

observational_model	Study_Count
Cohort	35
Case-Only	11
Case-Control	6
NA	5
Other	4
Case Control	2
Case-Crossover	1

Time Perspective

time_perspective	Study_Count
Prospective	58
Cross-Sectional	3
Retrospective	2
NA	1

Registries

Studies by Country

Country	Study_Count
Belgium|Finland|France|Germany|Italy|Netherlands|Romania|Spain|Turkey|United Kingdom	1
Belgium|France	1
France	1
Germany	1
Netherlands	1
Sweden	1
United Kingdom	1

Sites per Study

Site_count	Study_Count
1	5
10	1
12	1

Enrollment Metrics

Measure	Registries
Min	20.0000
1st Qu	93.0000
Median	947.0000
Mean	991.7143
3rd Qu	1816.5000
Max	2156.0000

Registry Model

observational_model	Study_Count
Cohort	6
Case-Control	1

Time Perspective

time_perspective	Study_Count
Prospective	5
Cross-Sectional	1
Other	1

Follow-up

target_duration	Study_Count
1 Day	2
1 Month	1
3 Months	1
30 Days	1
6 Months	1
7 Days	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02614001	Inspiratory Muscle Training in Stroke Patients With Stable Congestive Heart Failure: a Prospective RCT.	https://ClinicalTrials.gov/show/NCT02614001	Completed	Chang Gung Memorial Hospital	2012-05-31
NCT03388489	Mind-Body Walking Exercise for Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT03388489	Completed	National Taiwan University Hospital	2015-08-13
NCT03349437	Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients	https://ClinicalTrials.gov/show/NCT03349437	Completed	Philips Respironics	2018-02-20
NCT04370990	Automated Oxygen Administration -Rethinking Interventions Alleviating Dyspnea in Patients With COPD	https://ClinicalTrials.gov/show/NCT04370990	Recruiting	Copenhagen University Hospital, Hvidovre	2022-01-31
NCT04090671	Evaluation of the Multidimensional Dyspnea Profile (MDP)	https://ClinicalTrials.gov/show/NCT04090671	Recruiting	Institut für Pneumologie Hagen Ambrock eV	2020-01-01
NCT03367156	Dexamethasone in Controlling Dyspnea in Patients With Cancer	https://ClinicalTrials.gov/show/NCT03367156	Recruiting	M.D. Anderson Cancer Center	2021-10-31
NCT03885726	HVNI Ambulation Feasibility Study	https://ClinicalTrials.gov/show/NCT03885726	Completed	Vapotherm, Inc.	2019-02-28
NCT03824834	Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness	https://ClinicalTrials.gov/show/NCT03824834	Recruiting	McGill University	2020-06-30
NCT03240640	Effects of Inspiratory Muscle Training on Shortness of Breath (Dyspnea) and Postural Control in Patients With COPD	https://ClinicalTrials.gov/show/NCT03240640	Recruiting	KU Leuven	2019-12-31
NCT02357134	High-Flow Oxygen in Reducing Shortness of Breath Caused by Exercise in Patients With Cancer	https://ClinicalTrials.gov/show/NCT02357134	Active, not recruiting	M.D. Anderson Cancer Center	2020-05-31
NCT03137524	Fan Therapy in COPD Patients	https://ClinicalTrials.gov/show/NCT03137524	Completed	City, University of London	2017-07-26
NCT03056547	Biomarkers in Dyspnea	https://ClinicalTrials.gov/show/NCT03056547	Completed	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2019-01-08
NCT03035149	Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss	https://ClinicalTrials.gov/show/NCT03035149	Completed	University of Ottawa	2012-07-31
NCT03018756	Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea	https://ClinicalTrials.gov/show/NCT03018756	Active, not recruiting	Queen’s University	2018-06-25
NCT03012737	Palliation of Dyspnea With Mouth Piece Ventilation	https://ClinicalTrials.gov/show/NCT03012737	Recruiting	Tampere University Hospital	2019-12-31
NCT02998957	Acupoint Transcutaneous Electrical Nerve Stimulation in Hospitalized COPD Patients With Severe Dyspnoea	https://ClinicalTrials.gov/show/NCT02998957	Recruiting	Fundació Sant Joan de Déu	2019-06-30
NCT02977845	Effect of Qigong on the Symptom Clusters of Dyspnea, Fatigue, and Anxiety.	https://ClinicalTrials.gov/show/NCT02977845	Completed	Nam Dinh University of Nursing	2017-12-31
NCT02955108	The Effect of Distractive Auditory Stimuli (Music) on Dyspnea and Anxiety During Exercise in Adults With Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT02955108	Enrolling by invitation	NYU Langone Health	2020-03-31
NCT02932332	High-Flow Oxygen for Dyspnea in Hospitalized Cancer Patients	https://ClinicalTrials.gov/show/NCT02932332	Active, not recruiting	M.D. Anderson Cancer Center	2020-10-31
NCT02881866	Specificity of Dyspnoea Relief With Inhaled Furosemide	https://ClinicalTrials.gov/show/NCT02881866	Completed	Oxford Brookes University	2016-03-31
NCT02861508	Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department	https://ClinicalTrials.gov/show/NCT02861508	Completed	Yale University	2018-06-30
NCT02853123	Effect of Tiotropium + Olodaterol on Breathlessness in COPD Patients	https://ClinicalTrials.gov/show/NCT02853123	Completed	Boehringer Ingelheim	2017-07-24
NCT02801994	Impact of Proportional Assisted Ventilation on Dyspnea and Asynchrony in Mechanically Ventilated Patients	https://ClinicalTrials.gov/show/NCT02801994	Recruiting	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2019-10-31
NCT02801838	Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICU	https://ClinicalTrials.gov/show/NCT02801838	Completed	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2017-02-23
NCT02794909	AFrican Resuscitation Ultrasound In Critically-ill Adults	https://ClinicalTrials.gov/show/NCT02794909	Completed	University of Michigan	2017-01-31
NCT02792738	Effect of Hypnosis on Dyspnea	https://ClinicalTrials.gov/show/NCT02792738	Completed	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2016-09-13
NCT02622412	Evaluation of a Multi-professional Breathlessness Service for Patients With Breathlessness Due to Any Advanced Disease	https://ClinicalTrials.gov/show/NCT02622412	Completed	Ludwig-Maximilians - University of Munich	2019-02-01
NCT02622022	Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease	https://ClinicalTrials.gov/show/NCT02622022	Completed	University of Aarhus	2019-02-06
NCT02597478	Fentanyl Sublingual Spray for Exercise-Induced Breakthrough Dyspnea	https://ClinicalTrials.gov/show/NCT02597478	Active, not recruiting	M.D. Anderson Cancer Center	2020-01-31
NCT02567214	Ultibro® Versus Spiriva® Alone to Reduce Exertional Dyspnea in Patients With Moderate to Severe COPD	https://ClinicalTrials.gov/show/NCT02567214	Completed	Laval University	2018-11-30
NCT02538770	Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization	https://ClinicalTrials.gov/show/NCT02538770	Completed	University of Oulu	2015-11-30
NCT04434716	Monitoring and Self-management of Sleep Fatigue and Dyspnea	https://ClinicalTrials.gov/show/NCT04434716	Recruiting	University of Massachusetts, Amherst	2021-04-30
NCT02524054	Aerosol Inhalation Treatment for Dyspnea - Patients	https://ClinicalTrials.gov/show/NCT02524054	Completed	Beth Israel Deaconess Medical Center	2016-11-30
NCT02454751	The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial	https://ClinicalTrials.gov/show/NCT02454751	Completed	St. Boniface General Hospital Research Centre	2017-06-30
NCT02450825	Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration	https://ClinicalTrials.gov/show/NCT02450825	Completed	Centre hospitalier de l’Université de Montréal (CHUM)	2017-02-28
NCT02441868	Feasibility Testing of a Hospice Family Caregiver Intervention to Improve Patient Dyspnea Care	https://ClinicalTrials.gov/show/NCT02441868	Completed	Wayne State University	2018-04-30
NCT02445378	Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy	https://ClinicalTrials.gov/show/NCT02445378	Completed	Ohio State University Comprehensive Cancer Center	2016-09-30
NCT02429050	Morphine for Treatment of Dyspnea in Patients With COPD	https://ClinicalTrials.gov/show/NCT02429050	Completed	Maastricht University Medical Center	2019-03-06
NCT02364557	Standard of Care Therapy With or Without Stereotactic Radiosurgery and/or Surgery in Treating Patients With Limited Metastatic Breast Cancer	https://ClinicalTrials.gov/show/NCT02364557	Recruiting	NRG Oncology	2022-12-31
NCT02283892	Respiratory Complaints Checklist Trial	https://ClinicalTrials.gov/show/NCT02283892	Completed	Hospital de Clinicas de Porto Alegre	2016-01-31
NCT02248831	Evaluation of Cardiopulmonary Diseases by Ultrasound	https://ClinicalTrials.gov/show/NCT02248831	Completed	Echosense Ltd.	2018-05-31
NCT02172378	12-week Treatment With Inhaled Tiotropium (18 mcg Once Daily) on Lung Function and Static Lung Volumes in Stable, Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients. Correlation to Dyspnoea Scales	https://ClinicalTrials.gov/show/NCT02172378	Completed	Boehringer Ingelheim	2002-01-31
NCT02113839	Dyspnea in COPD: Relationship With Exacerbations Frequency	https://ClinicalTrials.gov/show/NCT02113839	Completed	Hospital Clinic of Barcelona	2014-08-31
NCT02105207	Comparison Between Lung Ultrasound and Chest Radiography for Acute Dyspnea	https://ClinicalTrials.gov/show/NCT02105207	Completed	University of Turin, Italy	2015-05-31
NCT02094950	Acupuncture Feasibility Trial for Dyspnea in Lung Cancer	https://ClinicalTrials.gov/show/NCT02094950	Completed	Abramson Cancer Center of the University of Pennsylvania	2015-07-15
NCT02082925	Dyspnea Threshold During 6 Minutes Walk Test	https://ClinicalTrials.gov/show/NCT02082925	Completed	5 Santé	2014-03-31
NCT02050282	Prehospital Triage of Patients With Severe Shortness of Breath Using Biomarkers	https://ClinicalTrials.gov/show/NCT02050282	Completed	University of Aarhus	2015-08-31
NCT02036762	STRETCH OF RESPIRATORY MUSCLES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE	https://ClinicalTrials.gov/show/NCT02036762	Completed	University of Sao Paulo	2014-01-31
NCT02012101	Non-invasive Mechanical Ventilation as a Rescue Therapy to Relieve Dyspnea in Patients With Stable Severe COPD	https://ClinicalTrials.gov/show/NCT02012101	Completed	Guangzhou Institute of Respiratory Disease	2014-04-30
NCT01985750	Understanding the Importance of Plasticity in the Brain Mechanisms of Dyspnoea Perception	https://ClinicalTrials.gov/show/NCT01985750	Recruiting	University of Oxford	2018-12-31
NCT04415957	Effects of the Elastic Tape on Dyspnea and Physical Activity in Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT04415957	Recruiting	University of Sao Paulo General Hospital	2020-11-01
NCT01286181	Device-guided Breathing for Shortness of Breath in COPD	https://ClinicalTrials.gov/show/NCT01286181	Completed	Mayo Clinic	2011-12-31
NCT01937637	Improving Management of Breathlessness in Patients With Lung Cancer	https://ClinicalTrials.gov/show/NCT01937637	Completed	Massachusetts General Hospital	2014-10-31
NCT01900873	Effects of Inspiratory Muscle Training on Dyspnea Perception During Exercise in Patients With COPD	https://ClinicalTrials.gov/show/NCT01900873	Completed	KU Leuven	2014-09-30
NCT01892553	Effect of Non Invasive Brain Stimulation on Experimentally Induced Dyspnea (Breathlessness)	https://ClinicalTrials.gov/show/NCT01892553	Completed	Centre d’Investigation Clinique et Technologique 805	2014-03-31
NCT01880528	Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer	https://ClinicalTrials.gov/show/NCT01880528	Completed	Mayo Clinic	2013-06-05
NCT01853449	Inhaled Fentanyl Citrate & Dyspnea	https://ClinicalTrials.gov/show/NCT01853449	Completed	McGill University	2014-08-31
NCT01852006	Abdominal Binding in Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT01852006	Completed	McGill University	2015-05-31
NCT01851993	Inhaled Ondansetron & Dyspnea	https://ClinicalTrials.gov/show/NCT01851993	Completed	McGill University	2014-09-30
NCT01856114	Fentanyl Buccal Tablets for Exercise Induced Breakthrough Dyspnea	https://ClinicalTrials.gov/show/NCT01856114	Completed	M.D. Anderson Cancer Center	2019-12-04
NCT01841515	Effect of Desmopressin on Platelet Function in CKD Patients on Antiplatelet Drug	https://ClinicalTrials.gov/show/NCT01841515	Completed	University of Ulsan	2013-04-30
NCT01831388	Breath Training Exercise for the Reduction of Chronic Dyspnea	https://ClinicalTrials.gov/show/NCT01831388	Completed	Memorial Sloan Kettering Cancer Center	2018-07-31
NCT01781793	Mechanisms of Exertional Dyspnea in Fibrotic Interstitial Lung Disease	https://ClinicalTrials.gov/show/NCT01781793	Completed	University of British Columbia	2016-04-30
NCT01760083	A Randomized Multicentre Trial to Evaluate the Utilization of Revascularization or Optimal Medical Therapy for the Treatment of Chronic Total Coronary Occlusions	https://ClinicalTrials.gov/show/NCT01760083	Completed	Euro CTO Club	2016-05-31
NCT01725828	Accuracy of Ultrasound in Identification of Cricothyroid Membrane: A Randomized Clinical Trial	https://ClinicalTrials.gov/show/NCT01725828	Completed	Samuel Lunenfeld Research Institute, Mount Sinai Hospital	2014-06-30
NCT01670097	Dexamethasone Dyspnea Study	https://ClinicalTrials.gov/show/NCT01670097	Active, not recruiting	M.D. Anderson Cancer Center	2021-01-31
NCT01644331	Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure	https://ClinicalTrials.gov/show/NCT01644331	Completed	Duke University	2016-02-29
NCT01604655	ProspEctive First Evaluation in Chest Pain Trial	https://ClinicalTrials.gov/show/NCT01604655	Completed	St. Luke’s-Roosevelt Hospital Center	2013-12-31
NCT01585883	Self-Management Intervention for Breathlessness in Lung Cancer	https://ClinicalTrials.gov/show/NCT01585883	Completed	University Health Network, Toronto	2015-12-30
NCT01580423	The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing	https://ClinicalTrials.gov/show/NCT01580423	Completed	Dartmouth-Hitchcock Medical Center	2013-03-31
NCT01577407	Non Opioid Treatment for Experimental Dyspnea	https://ClinicalTrials.gov/show/NCT01577407	Completed	Assistance Publique - Hôpitaux de Paris	2012-05-31
NCT01574066	Chest CT-scan for the Diagnosis of Community-acquired Pneumonia	https://ClinicalTrials.gov/show/NCT01574066	Completed	Assistance Publique - Hôpitaux de Paris	2012-12-31
NCT01545011	Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT01545011	Completed	University Hospital, Brest	2012-04-30
NCT01515566	Breakthrough Dyspnea Fentanyl Study in Cancer Patients	https://ClinicalTrials.gov/show/NCT01515566	Completed	M.D. Anderson Cancer Center	2013-04-30
NCT01513616	The Impact of Pulmonary Rehabilitation on Dyspnea in Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT01513616	Completed	Queen’s University	2011-12-31
NCT01510275	Combined Use of Respiratory Devices After Thoracic Surgery	https://ClinicalTrials.gov/show/NCT01510275	Completed	Villa Pineta Hospital	2012-06-30
NCT01490125	The Effect of QVA149 on Patient Reported Dyspnea in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT01490125	Completed	Novartis	2012-08-31
NCT01486394	Sonography in an Unselected Population of Acute Admitted Patients With Respiratory Symptoms	https://ClinicalTrials.gov/show/NCT01486394	Completed	Odense University Hospital	2013-04-30
NCT01461681	Improving Care of Patients With Heart Failure	https://ClinicalTrials.gov/show/NCT01461681	Completed	University of California, San Francisco	2013-09-30
NCT01440764	Aerosol Inhalation Treatment for Dyspnea	https://ClinicalTrials.gov/show/NCT01440764	Completed	Beth Israel Deaconess Medical Center	2016-04-30
NCT01378520	Effect of Ketoconazole on Breathlessness	https://ClinicalTrials.gov/show/NCT01378520	Completed	Dartmouth-Hitchcock Medical Center	2012-02-29
NCT01377051	Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea	https://ClinicalTrials.gov/show/NCT01377051	Completed	University of Milan	2011-08-31
NCT01364181	The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients	https://ClinicalTrials.gov/show/NCT01364181	Completed	Seoul National University Hospital	2011-03-31
NCT01345188	Ranolazine in Ischemic Cardiomyopathy	https://ClinicalTrials.gov/show/NCT01345188	Completed	Midwest Cardiovascular Research Foundation	2014-04-30
NCT01331187	Influence of Routinely Adding Ultrasound Screening in Medical Department	https://ClinicalTrials.gov/show/NCT01331187	Completed	Levanger Hospital	2011-06-30
NCT04378712	Hydrogen/Oxygen Mixed Gas Inhalation for Coronavirus Disease 2019 (COVID-19)	https://ClinicalTrials.gov/show/NCT04378712	Completed	Guangzhou Institute of Respiratory Disease	2020-03-23
NCT04373499	Virtual Teach-to-Goal Education vs. Brief Education for Children	https://ClinicalTrials.gov/show/NCT04373499	Active, not recruiting	University of Chicago	2020-02-27
NCT04186754	Study of an Integral Respiratory Rehabilitation Program in Oncological Patient With Disney	https://ClinicalTrials.gov/show/NCT04186754	Completed	University of Salamanca	2019-12-31
NCT03025425	Palliation of Dyspnea With Mouth Piece Ventilation in AECOPD	https://ClinicalTrials.gov/show/NCT03025425	Recruiting	Tampere University Hospital	2019-12-31
NCT04120142	Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients	https://ClinicalTrials.gov/show/NCT04120142	Completed	Faculty of Medicine, Sousse	2019-12-01
NCT04091334	Monitoring Patients With Shortness of Breath With Repeated Ultrasound Examinations	https://ClinicalTrials.gov/show/NCT04091334	Recruiting	Slagelse Hospital	2020-12-31
NCT02746536	Slow Chest Compression on Dynamic Hyperinflation, Dyspnea and Peripheral Muscle Deoxygenation in Patients With COPD	https://ClinicalTrials.gov/show/NCT02746536	Completed	University of the State of Santa Catarina	2017-06-30
NCT04051398	Effects of Transcutaneous Nerve Electrostimulation (TENS) of Acupuncture Points on Pulmonary Function and Dyspnea Symptoms in Patients With Pulmonary Nodules	https://ClinicalTrials.gov/show/NCT04051398	Recruiting	Hospital Santa Marcelina	2021-09-01
NCT04019236	Nursing Care for Breathing Discomfort Among Mechanically Ventilated Patients	https://ClinicalTrials.gov/show/NCT04019236	Recruiting	Assiut University	2019-12-31
NCT03998410	Evaluation of the Diagnostic Value of the TPD System in Determining ADHF Causing Acute Dyspnea	https://ClinicalTrials.gov/show/NCT03998410	Recruiting	Echosense Ltd.	2020-12-31
NCT03951779	Diagnostic Utility of Exercise Cardiac Magnetic Resonance in the Assessment of Cardiac Dyspnea.	https://ClinicalTrials.gov/show/NCT03951779	Enrolling by invitation	Mayo Clinic	2021-01-04
NCT03836547	Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity	https://ClinicalTrials.gov/show/NCT03836547	Enrolling by invitation	Mayo Clinic	2021-12-01
NCT03834363	Morphine or Fentanyl for Refractory Dyspnea in COPD	https://ClinicalTrials.gov/show/NCT03834363	Recruiting	University Medical Center Groningen	2021-01-31
NCT03728491	Education and Training Competences in Thoracic Ultrasound	https://ClinicalTrials.gov/show/NCT03728491	Recruiting	Odense University Hospital	2019-10-01
NCT03696524	Tunneled Pleural Catheters for Refractory Effusions Attributed to Congestive Heart Failure (TREAT-CHF) Trial	https://ClinicalTrials.gov/show/NCT03696524	Recruiting	University of California, Los Angeles	2020-05-01
NCT03674541	The Exercise Response to Pharmacologic Cholinergic Stimulation in Preload Failure	https://ClinicalTrials.gov/show/NCT03674541	Enrolling by invitation	Brigham and Women’s Hospital	2019-10-15
NCT03668483	Relation Between Muscle Strength With Exercise Capacity and Dyspnea in LTx	https://ClinicalTrials.gov/show/NCT03668483	Completed	Istanbul Medipol University Hospital	2019-08-01
NCT03653104	Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot	https://ClinicalTrials.gov/show/NCT03653104	Active, not recruiting	VA Quality Enhancement Research Intiative	2019-12-31
NCT03626519	Effects of Menthol on Dyspnoea in COPD Patients	https://ClinicalTrials.gov/show/NCT03626519	Recruiting	Groupe Hospitalier du Havre	2021-07-31
NCT03611127	The Impact of Early Pulmonary Rehabilitation on Multidimensional Aspect of Dyspnea in COPD Patients After Exacerbation	https://ClinicalTrials.gov/show/NCT03611127	Completed	Ain Shams University	2017-08-20
NCT03604822	Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS	https://ClinicalTrials.gov/show/NCT03604822	Active, not recruiting	Anglia Ruskin University	2018-07-31
NCT03568747	Efficacy and Mechanism of NIV in Relieving Dyspnea After Exercise in Patients With Stable Severe COPD	https://ClinicalTrials.gov/show/NCT03568747	Completed	Guangzhou Institute of Respiratory Disease	2019-02-03
NCT03517839	Assessment of Impact of Inspiratory Muscle Training on Movement Fear Due to Dyspnea in Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT03517839	Completed	Bezmialem Vakif University	2018-10-25
NCT03505697	The Effects of IMT on Exercise Capacity, Dyspnea and Lung Functions in LTx	https://ClinicalTrials.gov/show/NCT03505697	Completed	Istanbul Medipol University Hospital	2017-03-01
NCT03469037	Effects on Experimental Dyspnea of High Flow Nasal Cannula	https://ClinicalTrials.gov/show/NCT03469037	Completed	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2018-11-02
NCT03458182	Breathlessness During Exercise: Experience and Memory	https://ClinicalTrials.gov/show/NCT03458182	Completed	Skane University Hospital	2018-12-31
NCT03423888	High-flow Nasal Oxygen in Palliative Care: Pilot Study	https://ClinicalTrials.gov/show/NCT03423888	Recruiting	University Hospital, Toulouse	2020-06-30
NCT01193998	Impact of Validated Diagnostic Prediction Model of Acute Heart Failure in the Emergency Department	https://ClinicalTrials.gov/show/NCT01193998	Completed	St. Michael’s Hospital, Toronto	2014-06-30
NCT01188577	Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics	https://ClinicalTrials.gov/show/NCT01188577	Completed	Amphastar Pharmaceuticals, Inc.	2010-09-30
NCT01132846	Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study	https://ClinicalTrials.gov/show/NCT01132846	Completed	Duke University	2013-05-31
NCT01123902	Effectiveness of a Hand-held Fan for Breathlessness	https://ClinicalTrials.gov/show/NCT01123902	Completed	King’s College London	2008-02-29
NCT01051960	Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan	https://ClinicalTrials.gov/show/NCT01051960	Completed	University of California, Los Angeles	2010-06-30
NCT00984659	Validation of a New Shortness of Breath With Daily Activities Questionnaire in Patients With Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT00984659	Completed	GlaxoSmithKline	2010-07-01
NCT00975403	Pathophysiological Mechanisms of Dyspnea and Activity-limitation in Mild Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT00975403	Completed	Queen’s University	2012-09-30
NCT00982891	Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT00982891	Completed	Nova Scotia Health Authority	2012-06-30
NCT00974220	Effect of Inhaled Fentanyl on Dyspnea and Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT00974220	Completed	Queen’s University	2010-12-31
NCT00958919	Role of Endorphins in Perception of Dyspnea With Resistive Loading in Chronic Obstructive Pulmonary Disease (COPD)	https://ClinicalTrials.gov/show/NCT00958919	Completed	Dartmouth-Hitchcock Medical Center	2010-08-31
NCT00934128	High Flow Oxygen and Bilevel Airway Pressure for Persistent Dyspnea in Patients With Advanced Cancer	https://ClinicalTrials.gov/show/NCT00934128	Completed	M.D. Anderson Cancer Center	2012-11-30
NCT00904436	Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia	https://ClinicalTrials.gov/show/NCT00904436	Completed	VA Office of Research and Development	2001-01-31
NCT03679312	The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in COPD	https://ClinicalTrials.gov/show/NCT03679312	Recruiting	University of Alberta	2020-12-31
NCT02952027	Evaluating the Effectiveness of Incentive Spirometry	https://ClinicalTrials.gov/show/NCT02952027	Completed	Lifespan	2018-01-31
NCT04375917	Is Reduced Hypoxia Through a Robot Intervention, Associated With Sensory and Emotional Descriptions of Dyspnea, Anxiety, Depression, Symptom Burden and Anxiolytics	https://ClinicalTrials.gov/show/NCT04375917	Recruiting	Copenhagen University Hospital, Hvidovre	2022-01-01
NCT03953560	Symptom-related Screening for Early Detection of CTEPH.	https://ClinicalTrials.gov/show/NCT03953560	Recruiting	Hospitales Universitarios Virgen del Rocío	2019-12-31
NCT03575091	Physiotherapy for Infants With Breathing Difficulties	https://ClinicalTrials.gov/show/NCT03575091	Recruiting	Lund University	2021-05-31
NCT03222648	Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis	https://ClinicalTrials.gov/show/NCT03222648	Recruiting	University Hospital Southampton NHS Foundation Trust	2021-12-31
NCT01832402	Fentanyl Pectin Nasal Spray (FNPS) for Exercise-Induced Breakthrough Dyspnea	https://ClinicalTrials.gov/show/NCT01832402	Completed	M.D. Anderson Cancer Center	2019-11-25
NCT04093427	Influence of an Inverse Pressure Ramp in Long-term Non-invasive Ventilation on Dyspnea in the Morning After Therapy	https://ClinicalTrials.gov/show/NCT04093427	Recruiting	Wissenschaftliches Institut Bethanien e.V	2020-10-01
NCT03405090	Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators	https://ClinicalTrials.gov/show/NCT03405090	Recruiting	Queen’s University	2020-06-30
NCT03214809	The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams	https://ClinicalTrials.gov/show/NCT03214809	Recruiting	Rijnstate Hospital	2020-01-31
NCT03089125	Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer	https://ClinicalTrials.gov/show/NCT03089125	Recruiting	Massachusetts General Hospital	2021-02-01
NCT02720822	Breathlessness Exertion and Morphine Sulphate	https://ClinicalTrials.gov/show/NCT02720822	Completed	Flinders University	2019-12-20
NCT04019613	Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress Testing	https://ClinicalTrials.gov/show/NCT04019613	Active, not recruiting	Mayo Clinic	2021-10-31
NCT04010825	Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD.	https://ClinicalTrials.gov/show/NCT04010825	Recruiting	5 Santé	2021-06-30
NCT04393909	Improving Safety of Diagnosis and Therapy in the Inpatient Setting	https://ClinicalTrials.gov/show/NCT04393909	Recruiting	Brigham and Women’s Hospital	2021-06-30
NCT00974558	The Use of a Handheld Fan to Manage Breathlessness - A Feasibility Study	https://ClinicalTrials.gov/show/NCT00974558	Completed	Cambridge University Hospitals NHS Foundation Trust	2011-09-30
NCT00788788	Heliox in Experimental Upper Airway Obstruction	https://ClinicalTrials.gov/show/NCT00788788	Completed	University of Witten/Herdecke	2007-12-31
NCT00711438	Pilot Randomized Controlled Trial of a Breathlessness Intervention Service for Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT00711438	Completed	Cambridge University Hospitals NHS Foundation Trust	2007-04-30
NCT00636961	An Exploratory Study, to Assess the Effect of Repeat-dose Inhaled Indacaterol Maleate (300 μg) on Dynamic and Static Lung Hyperinflation, Subjective Breathlessness and Health Status in Patients With Chronic Obstructive Pulmonary Disease(COPD)	https://ClinicalTrials.gov/show/NCT00636961	Completed	Novartis	2008-08-31
NCT00554580	Continuous Positive Airway Pressure for Acute Pulmonary Edema	https://ClinicalTrials.gov/show/NCT00554580	Completed	Assistance Publique - Hôpitaux de Paris	2008-07-31
NCT00512811	Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients	https://ClinicalTrials.gov/show/NCT00512811	Completed	Baqiyatallah Medical Sciences University	NA
NCT00491777	Correlation Research Study: IQ2, NcIQ and IQ101	https://ClinicalTrials.gov/show/NCT00491777	Completed	Noninvasive Medical Technologies, Inc.	NA
NCT00461162	Dyspnea Self-Management: Internet or Face-to-Face	https://ClinicalTrials.gov/show/NCT00461162	Completed	University of California, San Francisco	2011-08-31
NCT00458419	Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT00458419	Completed	Dartmouth-Hitchcock Medical Center	NA
NCT00410293	NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs	https://ClinicalTrials.gov/show/NCT00410293	Completed	Erasmus Medical Center	NA
NCT00338481	“Red Morphine Drops” for Symptomatic Treatment of Dyspnoea in Lung Cancer	https://ClinicalTrials.gov/show/NCT00338481	Completed	Sankt Lukas Hospice	2011-02-28
NCT00327873	Palliative Oxygen for the Relief of Breathlessness	https://ClinicalTrials.gov/show/NCT00327873	Completed	National Institute on Aging (NIA)	2008-03-31
NCT00270387	A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy	https://ClinicalTrials.gov/show/NCT00270387	Completed	Scios, Inc.	NA
NCT00243282	Randomized Controlled Trial of Mind-Body Breathing Therapy (in Chronic Obstructive Pulmonary Disease) To Improve Palliation of Dyspnea and Health-Related Quality of Life	https://ClinicalTrials.gov/show/NCT00243282	Completed	VA Office of Research and Development	NA
NCT00234286	Intervention to Improve Care at Life’s End	https://ClinicalTrials.gov/show/NCT00234286	Completed	VA Office of Research and Development	2011-03-31
NCT00206830	SHORTness of Breath In the Emergency Department (SHORTIE)	https://ClinicalTrials.gov/show/NCT00206830	Completed	Biosite	2006-08-31
NCT00206609	The Role of Oxygen in the Management of Dyspnoea in Advanced Cancer	https://ClinicalTrials.gov/show/NCT00206609	Completed	Bayside Health	NA
NCT00188435	Comparison of CXR and MnDCT	https://ClinicalTrials.gov/show/NCT00188435	Completed	University Health Network, Toronto	NA
NCT00067691	Acupuncture for Shortness of Breath in Cancer Patients	https://ClinicalTrials.gov/show/NCT00067691	Completed	National Center for Complementary and Integrative Health (NCCIH)	NA
NCT00053846	Buspirone in Reducing Shortness of Breath in Patients With Cancer	https://ClinicalTrials.gov/show/NCT00053846	Completed	University of Rochester	2010-11-30
NCT00043836	The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure	https://ClinicalTrials.gov/show/NCT00043836	Completed	Synvista Therapeutics, Inc	2003-02-28
NCT00274027	Mechanisms of Dyspnea Relief During Exercise in COPD Patients Following Treatment With Tiotropium (Spiriva)	https://ClinicalTrials.gov/show/NCT00274027	Completed	Boehringer Ingelheim	2003-03-31
NCT00130611	B-type Natriuretic Peptide for Acute Shortness of Breath EvaLuation (BASEL) Study - Private Practice	https://ClinicalTrials.gov/show/NCT00130611	Completed	University Hospital, Basel, Switzerland	2010-01-31
NCT00289276	FAST (Fluid Accumulation Status Trial)	https://ClinicalTrials.gov/show/NCT00289276	Completed	Medtronic Cardiac Rhythm and Heart Failure	2008-04-30
NCT00102401	Internet-Based and Established Dyspnea Self-Management Programs in Chronic Obstructive Pulmonary Disease (COPD) Patients	https://ClinicalTrials.gov/show/NCT00102401	Completed	Robert Wood Johnson Foundation	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT00833144	Bedside Ultrasound Identifies Congestive Heart Failure	https://ClinicalTrials.gov/show/NCT00833144	Completed	Emory University	2010-02-28
NCT03239730	Arterial pH Selectively Predicts Intensive Care Unit Transfer From the Emergency Department in Obese Patients With Acute Dyspnea	https://ClinicalTrials.gov/show/NCT03239730	Completed	Association pour la Formation du Personnel à la Medecine d’Urgence	2014-05-30
NCT03194243	Pathway and Urgent caRe of Dyspneic Patient at the Emergency Department in LorrainE District (PURPLE)	https://ClinicalTrials.gov/show/NCT03194243	Recruiting	Central Hospital, Nancy, France	2023-10-31
NCT03048032	Lithuanian Echocardiography Study of Dyspnea in Acute Settings	https://ClinicalTrials.gov/show/NCT03048032	Completed	Vilnius University	2017-12-31
NCT02863666	Verification of Prediction Algorithm	https://ClinicalTrials.gov/show/NCT02863666	Completed	Zoll Medical Corporation	2017-12-13
NCT02835963	Acute Heart Failure Study in Patients Admitted to Emergency Department for Dyspnea	https://ClinicalTrials.gov/show/NCT02835963	Completed	University Hospital, Toulouse	2016-08-31
NCT02800122	PAthwAy of Dyspneic patIent in Emergency (PArADIsE)	https://ClinicalTrials.gov/show/NCT02800122	Enrolling by invitation	Central Hospital, Nancy, France	2018-12-31
NCT02719509	Emergency Department Cardiac Ultrasound	https://ClinicalTrials.gov/show/NCT02719509	Completed	Hennepin Healthcare Research Institute	2016-06-30
NCT02710383	Biomarker for Cystic Fibrosis	https://ClinicalTrials.gov/show/NCT02710383	Recruiting	Centogene AG Rostock	2023-12-31
NCT02638649	Prehospital Use of Ultrasound in Undifferentiated Shortness of Breath	https://ClinicalTrials.gov/show/NCT02638649	Completed	Yale University	2018-09-15
NCT02632851	Treatment of Respiratory Tract Infection and/or Acute Bronchitis With Ectoin Inhalation Solution	https://ClinicalTrials.gov/show/NCT02632851	Completed	Bitop AG	2016-05-31
NCT02555202	Validation of French Version of LCADL and Dyspnea-12	https://ClinicalTrials.gov/show/NCT02555202	Completed	University Hospital, Brest	2016-09-30
NCT02336464	Impact of Dyspnea on Patients in the Intensive Care Unit	https://ClinicalTrials.gov/show/NCT02336464	Completed	Assistance Publique - Hôpitaux de Paris	2018-04-13
NCT02229994	Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT02229994	Completed	Assistance Publique - Hôpitaux de Paris	2014-03-27
NCT02187770	Precision of IMED-4 Lung Fluid Measurements	https://ClinicalTrials.gov/show/NCT02187770	Completed	Intersection Medical, Inc.	2015-09-30
NCT02114944	Treatment of Dyspnea in Do-not-intubate Patients	https://ClinicalTrials.gov/show/NCT02114944	Active, not recruiting	Tufts Medical Center	2019-03-01
NCT02111525	Fluid Status of Outpatients With Dyspnea	https://ClinicalTrials.gov/show/NCT02111525	Completed	Intersection Medical, Inc.	2015-09-30
NCT01287429	Lung Ultrasound for Acute Dyspnea in Emergency Department	https://ClinicalTrials.gov/show/NCT01287429	Completed	University of Turin, Italy	2012-10-31
NCT01276275	Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel	https://ClinicalTrials.gov/show/NCT01276275	Completed	AstraZeneca	2015-04-30
NCT02055443	Myocardial Ischemia Detection for Early Identification of Patients With Ischemic Chest Pain	https://ClinicalTrials.gov/show/NCT02055443	Completed	University of Pittsburgh	2016-12-31
NCT04454554	Prevalence of Pulmonary Embolism in Patients With Dyspnea on Exertion (PEDIS)	https://ClinicalTrials.gov/show/NCT04454554	Recruiting	Arianna Anticoagulazione Foundation	2020-09-24
NCT02161445	Systolic Time Intervals in the Diagnosis of Heart Failure in Emergency Departement	https://ClinicalTrials.gov/show/NCT02161445	Completed	University of Monastir	2017-12-31
NCT03356288	The General Breathing Record Study	https://ClinicalTrials.gov/show/NCT03356288	Completed	Cambridge Respiratory Innovations Limited	2018-07-04
NCT01197586	Evaluation of Surfactant Protein B in the Differential Diagnostics of Dyspnea	https://ClinicalTrials.gov/show/NCT01197586	Completed	Universitätsmedizin Mannheim	2011-12-31
NCT01831115	Basics in Acute Shortness of Breath EvaLuation (BASEL V) Study	https://ClinicalTrials.gov/show/NCT01831115	Active, not recruiting	University Hospital, Basel, Switzerland	2015-08-31
NCT01662843	BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath	https://ClinicalTrials.gov/show/NCT01662843	Completed	Eastern Virginia Medical School	2012-05-31
NCT01601288	Database of All Patients Who Have Undergone Pulmonary Function Testing at Singapore General Hospital	https://ClinicalTrials.gov/show/NCT01601288	Completed	Singapore General Hospital	2017-12-31
NCT01418248	Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease	https://ClinicalTrials.gov/show/NCT01418248	Completed	Mayo Clinic	2013-08-31
NCT04327882	Point-of-care Ultrasound Interest in Dyspneic Emergency Department Patients: an Observational Bicentric Study	https://ClinicalTrials.gov/show/NCT04327882	Recruiting	Centre Hospitalier Universitaire de NÄ«mes	2021-03-16
NCT04267029	Transfusion Associated Dyspnea Profiling	https://ClinicalTrials.gov/show/NCT04267029	Recruiting	Toronto Transfusion Medicine Collaborative	2021-01-01
NCT04240067	Multimarker Approach for Acute Dyspnea in Elderly Patients Admitted in the Emergency Department	https://ClinicalTrials.gov/show/NCT04240067	Recruiting	Centre Hospitalier Universitaire de Besancon	2022-12-31
NCT04236934	Thoracentesis: Symptoms and Prediction of the Need for Therapeutic Thoracentesis	https://ClinicalTrials.gov/show/NCT04236934	Recruiting	Naestved Hospital	2021-08-13
NCT04119505	Value of Diaphragmatic Motion Measurement at Ultrasonography to Predict Poor Prognosis in Emergency Department Patients With Acute Respiratory Failure	https://ClinicalTrials.gov/show/NCT04119505	Recruiting	University Hospital, Montpellier	2020-11-01
NCT04029051	Focus Thoracic Ultrasound for Dyspnea Diagnosis in Elderly Patient in the Emergency Department	https://ClinicalTrials.gov/show/NCT04029051	Completed	Nantes University Hospital	2019-06-01
NCT03905460	Point-of-care Ultrasound in Prehospital Dyspnea	https://ClinicalTrials.gov/show/NCT03905460	Recruiting	University of Aarhus	2021-05-01
NCT03880084	Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM)	https://ClinicalTrials.gov/show/NCT03880084	Recruiting	University of Modena and Reggio Emilia	2020-04-01
NCT03773991	Dyspnea Assessment in Hemodialysis Patients	https://ClinicalTrials.gov/show/NCT03773991	Recruiting	Lawson Health Research Institute	2020-12-31
NCT03672994	Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient	https://ClinicalTrials.gov/show/NCT03672994	Completed	University of Leicester	2018-12-30
NCT03660592	Reproducibility of Lung Ultrasound in the Diagnosis of Acute Heart Failure in the ED	https://ClinicalTrials.gov/show/NCT03660592	Completed	University of Monastir	2017-01-01
NCT03623204	Evolution of Dyspnea After Bariatric Surgery in Patient With Obesity	https://ClinicalTrials.gov/show/NCT03623204	Completed	CHU de Reims	2015-10-01
NCT03621098	EMPOWER-PULM (PULMonary Outcomes in Older Adults Empowered With Movement to Prevent Obesity and Weight Regain)	https://ClinicalTrials.gov/show/NCT03621098	Completed	Wake Forest University Health Sciences	2018-11-19
NCT03598569	Auto-evaluation of Dyspnea	https://ClinicalTrials.gov/show/NCT03598569	Completed	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	2013-07-31
NCT03550235	Exploration of Dyspnea at Non-high Brain Natriuretic Peptide (BNP)	https://ClinicalTrials.gov/show/NCT03550235	Recruiting	Assistance Publique - Hôpitaux de Paris	2020-10-31
NCT03467815	Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease	https://ClinicalTrials.gov/show/NCT03467815	Completed	Bispebjerg Hospital	2018-06-07
NCT01235182	Ultrasound in Acute Dyspnea in the Field	https://ClinicalTrials.gov/show/NCT01235182	Completed	University Medical Centre Maribor	2010-04-30
NCT01227317	BIOmarkers of Dyspnea IN Emergency Room	https://ClinicalTrials.gov/show/NCT01227317	Completed	ThermoFisher Scientific Brahms Biomarkers France	2011-08-31
NCT01138358	Study of Episodic Breathlessness in Patients With Lung Cancer or Other Advanced Disease	https://ClinicalTrials.gov/show/NCT01138358	Completed	National Cancer Institute (NCI)	2010-08-31
NCT01081210	Screening of Patients Admitted to a Local Hospital With Pocket-sized Ultrasound	https://ClinicalTrials.gov/show/NCT01081210	Completed	Levanger Hospital	2010-09-30
NCT00878475	Dyspnea and Biomarkers in a Prehospital Setting	https://ClinicalTrials.gov/show/NCT00878475	Completed	Health Care Center Maribor	2007-06-30
NCT03717779	Contribution LUS in the Diagnosis of Acute Heart Failure (AHF) in Patients Admitted to the ED	https://ClinicalTrials.gov/show/NCT03717779	Completed	University of Monastir	2017-10-01
NCT03092700	Pulmonary Rehabilitation, Dyspnoea and Emotional Cognition in COPD	https://ClinicalTrials.gov/show/NCT03092700	Recruiting	Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil	2020-10-31
NCT01399541	Recovery and Rehabilitation After Lung Cancer Surgery	https://ClinicalTrials.gov/show/NCT01399541	Completed	Oslo University Hospital	2014-04-30
NCT01154517	Utility of the History and Physical Exam in the Emergency Department	https://ClinicalTrials.gov/show/NCT01154517	Completed	Henry Ford Health System	2010-06-30
NCT02771262	Making Sense of Dyspnea Assessment	https://ClinicalTrials.gov/show/NCT02771262	Completed	NYU Langone Health	2019-08-02
NCT02122640	Evaluation of Acute Cardiogenic Dyspnoea With Thorax Echography and Pro-BNP in the Emergency Department	https://ClinicalTrials.gov/show/NCT02122640	Completed	Comitato Etico di Area Vasta Sud Est	2013-02-28
NCT04449081	Knowledge, Attitude and Practice of Dental Students About COVID-19	https://ClinicalTrials.gov/show/NCT04449081	Completed	Melaka Manipal Medical College	2020-06-10
NCT03831204	Systolic Time Intervals a Prognostic Tool of Heart Failure in Emergency Departement (STI/AHF)	https://ClinicalTrials.gov/show/NCT03831204	Completed	University of Monastir	2017-06-30
NCT03517826	Validity and Reliability of The Turkish Version of Breathlessness Beliefs Questionnaire	https://ClinicalTrials.gov/show/NCT03517826	Completed	Bezmialem Vakif University	2018-11-01
NCT03192865	Diaphragmatic Paralysis in Arthroscopic Shoulder Surgery	https://ClinicalTrials.gov/show/NCT03192865	Completed	Clinique Medipole Garonne	2014-10-02
NCT03786367	Dyspnea in Chronic Thromboembolic Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT03786367	Recruiting	Queen’s University	2020-03-31
NCT00611182	Dyspnea in Patients With Pulmonary Fibrosis	https://ClinicalTrials.gov/show/NCT00611182	Completed	University of California, San Francisco	2010-03-31
NCT00540163	Observational Non-interventional Study With Spiriva in Chronic Obstructive Pulmonary Disease Patients With Exercise-induced Dyspnoea	https://ClinicalTrials.gov/show/NCT00540163	Completed	Boehringer Ingelheim	2007-11-30
NCT00537628	Biomarkers in Acute Heart Failure	https://ClinicalTrials.gov/show/NCT00537628	Completed	Brahms AG	2008-05-31
NCT00906867	Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)	https://ClinicalTrials.gov/show/NCT00906867	Completed	Johann Wolfgang Goethe University Hospital	2010-02-28

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02360540	PERCEPIC: PERC Rule Combined With Implicit Low Clinical Probability	https://ClinicalTrials.gov/show/NCT02360540	Completed	University Hospital, Angers	2016-07-31
NCT02060799	European Dyspnoea Survey in the EMergency Departments	https://ClinicalTrials.gov/show/NCT02060799	Completed	Hopital Lariboisière	2014-03-31
NCT01949402	A New Way of Looking at Your Lungs	https://ClinicalTrials.gov/show/NCT01949402	Completed	University of Oxford	2016-07-31
NCT01910233	Registry of Patients With Acute Dyspnea in the Emergency Department	https://ClinicalTrials.gov/show/NCT01910233	Completed	Klinikum Nürnberg	2015-05-31
NCT04422587	Evaluation of the COVID-19 Infection Response in Patients Admitted to the Emergency Department for Dyspnea	https://ClinicalTrials.gov/show/NCT04422587	Active, not recruiting	University Hospital, Toulouse	2020-06-05
NCT03503123	Deventilation Dyspnea in COPD Patients Using NIV	https://ClinicalTrials.gov/show/NCT03503123	Recruiting	University Medical Center Groningen	2022-12-15
NCT03468205	The Relating Experienced To Recalled Breathlessness Observational Study	https://ClinicalTrials.gov/show/NCT03468205	Recruiting	Skane University Hospital	2019-12-31